Abstract: The acid pressure oxidation of refractory gold concentrate was studied, and the effect of temperature on the oxidation of sulfide minerals, the migration of element and gold cyanide leaching were studied. Experimental results show that the reaction rate of pyrite and arsenopyrite was influenced by temperature, the highest gold cyanide leaching rate (94%) was obtained at 215℃. In the solid phase, pyrite and arsenopyrite had transformed gradually into Ferric arsenate or the co-deposition that was containing iron, arsenic, sulfur, silicon, and other elements. The precipitation produced during the reaction had no significant effect on cyanide leaching.