Abstract: This is an article in the field of mineral processing engineering. Barium slag is toxic solid waste, and a large amount of barium slag is piled up to seriously harm the environment and cause huge waste of national land resources. Acid-dissolving barium in acid leaching barium residue is one of the best ways to dispose of barium residue and recover barium. The paper adopts the flotation process to recover the barium sulfate in the acid leaching tailings of the enriched barium slag, in order to realize the comprehensive recovery of barium resources in the barium slag. The experimental research of the flotation recovery of barium residue acid leaching residue shows that. Under the condition that the amount of sodium carbonate is 2000 g/t, the amount of sodium silicate is 500 g/t and the amount of sodium oleate is 3000 g/t, through the flotation closed-circuit process of one roughing, four beneficiation, and two sweeping. Obtained the flotation index of 85.38% barite concentrate grade and 69.35% recovery rate. Concentrate products meet the barite standards used in the industrial production of barium carbonate.