Abstract: This is an essay in the field of mineral processing engineering. The main minerals in tantalum niobium tailings in Jiangxi Province are feldspar, quartz, lithionite and topaz, containing a small amount of spodumene and sericite, among which the main available minerals are lithionite. For a long time, the tailings lack a comprehensive utilization and recycling process. This test study studies the flotation test of the main available mineral lithium mica in the tailings, determines the reasonable beneficiation recovery process, and provides a technical basis for the comprehensive utilization of the tailings. According to the process mineralogy properties of the ore, the lithium mica was recovered. Through a series of flotation condition tests, HZ-00 and dodecylamine are used as the combination catcher, Na₂CO₃ is pH value adjustment agent, water glass as the inhibitor, the flotation process of "one coarse, one sweep and one fine", the flotation closed circuit test can obtain Li₂O grade of 4.3.02%, the recovery rate of 72.41%, and the test results are relatively ideal.