Abstract: This is an essay in the field of mining engineering. The crystal characteristics of spodumene are the endogenous factors that determine the floatability. The collector is an exogenous factor that determines floatability of spodumene. In the flotation process, the common metal ions have an important influence on the performance of spodumene collector. In this essay, the factors affecting the flotation behavior of spodumene are introduced and summarized from the crystal characteristics of spodumene and the effect of external metal ions on the common spodumene collector in industrial production. Firstly, the surface crystal characteristics of spodumene are summarized, and the effect of the active site of spodumene surface crystal on flotation behavior is summarized. Secondly, the effects of common metal ions on the properties of oleic acid, hydroxamic acid, amine and anion-cation complex collectors commonly used in industrial production are summarized. Studies have shown that Ca²⁺, Fe³⁺ and Mg²⁺ can improve the performance of oleic acid collectors. Pb²⁺ can improve the performance of hydroxamic acid collectors. Ca²⁺ can improve the performance of amine collectors. The effect of amine collector and spodumene can be inhibited by an iron ball milling medium. This study has theoretical and practical significance for improving the separation efficiency of spodumene and using spodumene collector efficiently.