Abstract: The Panxi-Huidong Area in China is a significant large-scale rutile ore cluster, whose metallogenic mechanisms and resource potential are crucial for ensuring the supply of strategic titanium resources. This study systematically reveals the geological characteristics and metallogenic patterns of rutile deposits through field geological surveys and petrographic studies, while proposing exploration strategies. Key findings include: (1) Ore bodies are strictly controlled by the metamorphic volcanic-sedimentary rocks of the lower Tiantang Formation (Pt₃t) in the pre-Sinian system, with sericite phyllite and chlorite-sericite phyllite as the main ore-bearing formations, derived from calc-alkaline volcanic tuff that provided the primary material source; (2) Rutile exhibits typical metamorphic differentiation characteristics, being directionally distributed along the (001) cleavage planes of micas; (3) The genesis of the deposits is attributed to a volcanic sedimentation-regional metamorphism superimposed type; (4) A "geochemical-geophysical" prospecting methodology is proposed, prioritizing hinge zones of composite anticlines, schistosity-dense zones, and CSAMT low-resistivity anomalies as key exploration targets. This research establishes a new paradigm for studying Precambrian titanium metallogenic systems on the western margin of the Yangtze Block and provides critical guidance for breakthroughs in deep mineral exploration.