Abstract: In this study, the process mineralogy of a copper-nickel polymetallic sulfide ore was studied. Results show that the main useful minerals in the ore are nickel-pyrite and chalcopyrite. The main metal sulfides are pyrrhotite and a small amount of pyrite. The gangue minerals are mainly magnesium silicate minerals such as serpentine, olivine and actinolite. The ore has a high comprehensive recycling value. It is recommended to carry out research on the occurrence state of platinum, palladium, gold and silver and the corresponding beneficiation process to maximize the recovery of precious metal minerals in the ore.