Abstract: In order to alleviate the shortage of natural sand and gravel resources, an orthogonal test was used to study the mechanics of recycled concrete from gold tailings. Four influencing factors of water-cement ratio, gold tailing sand substitution rate, recycled coarse aggregate substitution rate and fly ash content were selected, and two performance indicators of compressive strength and tensile strength of gold tailing sand recycled concrete were obtained. The performance was also researched on the ratio optimization combination. Results showed that the water-cement ratio and the content of fly ash have significant effects on the two evaluation indexes, followed by the replacement rate of gold tailing sand, while the reclaimed coarse aggregate of secondary crushing has little effect on the two indexes. The optimal factor level scheme for the preparation of recycled concrete with gold tailing sand is the water-cement ratio of 0.45, the replacement rate of gold tailing sand, the replacement rate of recycled coarse aggregate of 30% and the content of fly ash of 10%. By comparing the strength of recycled concrete with ordinary concrete and recycled concrete with the best ratio of gold tailing sand, it can be seen that it is feasible to use gold tailing sand in recycled concrete.