Abstract: High-purity quartz, famous for low impurities and high purity, has been widely used in optical fiber communication, photovoltaic, aerospace, semiconductor displayand other high-tech industries. Aluminosilicate mineral is one of the most typical gangue minerals in quartz ore, mainly including potassium, albite, mica, etc. With the existing conventional separation process, it is difficult to effectively and efficiently remove these intractable trace and micro-fine feldspar and mica. In this paper, the basic status of separation of aluminosilicate gangue minerals from high-purity quartz is described in detail, and the frontier technology of activation and separation of refractory trace and micro-fine feldspar and mica is systematically summarized. Based on the research progress of the basic theory of high-purity quartz in China in recent years, some reasonable scientific suggestions are put forward for the separation of micro-and micro-fine aluminosilicate gangue minerals in the crystal interface and inner encapsulation of high-quality quartz.