Abstract: The total cyanide and arsenic in a cyanide residue of a gold mine exceed the standard requirements. The process of hydrogen peroxide oxidation decomposition cyanide and ferrous sulfate complexation fixation arsenic is studied. The results showed that in the cyanogen removal section, the amount of hydrogen peroxide added was 2 ml/L, the reaction time was 2 h, in the arsenic fixation section, the amount of ferrous sulfate added was 0.5 g/L, the amount of hydrogen peroxide added was 1 ml/L, the amount of sulfuric acid added was 6.5 ml/L, and the reaction time was 1 h. After the treatment of cyanide removal and arsenic fixation, the total cyanide concentration and arsenic concentration in the toxic leaching solution of the cyanogen residue are 0.25 mg/L and 0.55 mg/L, which meets the standard requirements and can be stored in the tailings pond.