Abstract: In order to improve the comprehensive utilization rate of V₂O₅ form vanadium titanomagnetite concentrates, the direct leaching and the roasting-leaching tests were carried out using titanium white waste acid byorthogonal experiment method. The results of direct leaching experiment show that the liquid-solid ratio is the most important factor affecting the leaching rate of V₂O₅, and the concentration of titanium white waste acid is the least. The 71.05% vanadium can be leached under the experimental condition of 20% of titanium white waste acid, 90℃ for 90 min with a liquid-to-solid ratio of 5. The results of roasting-leaching experiment show that the effects of roasting temperature, K₂CO₃ ratio, Na₂CO₃ ratio and roasting time on the leaching rate of V₂O₅ are from large to small. When the conditions of roasting time of 2 h, roasting temperature of 1000℃, Na₂CO₃ ratio of 10%, and K₂CO₃ ratio of 10%, and the leaching rate of V₂O₅ can reach 84.48%.